治疗
DPDR目前尚无统一标准治疗方案，现有研究探索了多种干预手段。本分类收录DPDR治疗相关的随机对照试验、案例报告和综述文献，涵盖氯米帕明、拉莫三嗪、rTMS、tDCS、舞蹈/运动疗法、认知行为疗法及中医辨证论治等方法。
文献列表
[1] Randomized trial of a generative AI chatbot for mental health treatment
作者: Heinz M.; Mackin D.; Trudeau B.; Bhattacharya S.
年份: 2025
DOI: 10.1056/AIoa2400802
原文链接: https://ai.nejm.org/doi/abs/10.1056/AIoa2400802
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1056/AIoa2400802](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1056/AIoa2400802)
摘要（中文）: 本随机对照试验测试了专家微调的生成式AI治疗聊天机器人Therabot对心理健康治疗的效果。210名MDD、GAD或CHR-FED成人受试者接受4周干预，结果显示AI聊天机器人可显著减轻抑郁、焦虑和早期功能退化症状。
摘要（英文）: We present a randomized controlled trial (RCT) testing an expert-fine-tuned Gen-AI-powered chatbot, Therabot, for mental health treatment. N = 210 adults with MDD, GAD, or CHR-FED. 4-week Therabot vs waitlist control. Results showed significant reductions in MDD (d = 0.845-0.903), GAD (d = 0.794-0.840), and CHR-FED (d = 0.627-0.819) symptoms. First RCT demonstrating effectiveness of a fully Gen-AI therapy chatbot for clinical-level mental health symptoms.
一句话概括: 生成式AI聊天机器人Therabot可显著改善抑郁、焦虑和早期功能退化症状。
[2] 中医辨治人格解体神经症
作者:
年份: 2010
DOI: 无
原文链接: [https://kns.cnki.net/kcms/detail/detail.aspx?dbcode = CJFD&dbname = CJFD2010&filename = HNZY201011029&v = L%25mmd2FD5VKGKnSBDDa7CYkkc6GN2cRNRBpPjVdTJVRh18oLCiR4%25mmd2B3o%25mmd2F7SexrC%25mmd2FdjM1q6](https://kns.cnki.net/kcms/detail/detail.aspx?dbcode = CJFD&dbname = CJFD2010&filename = HNZY201011029&v = L%25mmd2FD5VKGKnSBDDa7CYkkc6GN2cRNRBpPjVdTJVRh18oLCiR4%25mmd2B3o%25mmd2F7SexrC%25mmd2FdjM1q6)
PubMed: 无
摘要（中文）: 人格解体神经症以非真实感和自身或环境疏远感为突出表现，中医分为心血虚、痰湿内蒙、痰瘀阻抑三型，治以补血养心、化痰启上、涤痰化瘀，注重养心持神、健脾益气、防止复发。
摘要（英文）: 人格解体神经症系以非真实感和同自身或环境的疏远感为突出表现的一种神经官能症,临床可分为心血虚、痰湿内蒙、痰瘀阻抑3种证型,以补血养心,化痰启上,涤痰化瘀为治则,注重养心持神,健脾益气,防止复发,方可取得较好的疗效。
一句话概括: 中医将人格解体分为三型，辨证施治可获较好疗效。
[3] Repetitive transcranial magnetic stimulation improves depersonalization: A case report
作者: Jiménez-Genchi A.
年份: 2004
DOI: 10.1017/S1092852900009366
原文链接: [https://www.embase.com/search/results?subaction = viewrecord&id = L38649726&from = export http://dx.doi.org/10.1017/S1092852900009366](https://www.embase.com/search/results?subaction = viewrecord&id = L38649726&from = export)
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1017/S1092852900009366](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1017/S1092852900009366)
摘要（中文）: 本案例报告描述了一名去人格化障碍患者接受左侧背外侧前额皮质6次重复经颅磁刺激治疗，去人格化评分降低28%。
摘要（英文）: Depersonalization disorder is a poorly understood and treatment-resistant condition. This report describes a patient with depersonalization disorder who underwent six sessions of repetitive transcranial magnetic stimulation on the left dorsolateral prefrontal cortex. Repetitive transcranial magnetic stimulation produced a 28% reduction on depersonalization scores.
一句话概括: rTMS刺激左侧DLPFC可改善DPD症状，评分降低28%。
[4] Ventrolateral prefrontal cortex repetitive transcranial magnetic stimulation in the treatment of depersonalization disorder: A consecutive case series
作者: Jay E.; Nestler S.; Sierra M.; McClelland J.; Kekic M.; David A.
年份: 2016
DOI: 10.1016/j.psychres.2016.04.027
原文链接: [https://www.embase.com/search/results?subaction = viewrecord&id = L609924941&from = export http://dx.doi.org/10.1016/j.psychres.2016.04.027](https://www.embase.com/search/results?subaction = viewrecord&id = L609924941&from = export)
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1016/j.psychres.2016.04.027](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1016/j.psychres.2016.04.027)
摘要（中文）: 7名耐药DPD患者接受右侧腹外侧前额皮质20次rTMS治疗，去人格化症状平均降低44%（范围2-83.5%），2例完全应答、4例部分应答、1例无应答。应答通常出现在前6次治疗，且无明显不良反应。
摘要（英文）: Case reports and an open trial have reported promising responses to repetitive transcranial magnetic stimulation (rTMS) to prefrontal and temporo-parietal sites in patients with depersonalization disorder (DPD). We recently showed that a single session of rTMS to the ventrolateral prefrontal cortex (VLPFC) was associated with a reduction in symptoms and increase in physiological arousal. Seven patients with medication-resistant DSM-IV DPD received up to 20 sessions of right-sided rTMS to the VLPFC for 10 weeks. Stimulation was guided using neuronavigation software based on participants' individual structural MRIs, and delivered at 110% of resting motor threshold. A session consisted of 1 Hz repetitive TMS for 15 min. The primary outcome measure was reduction in depersonalization symptoms on the Cambridge Depersonalization Scale (CDS). Secondary outcomes included scores on the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). 20 sessions of rTMS treatment to right VLPFC significantly reduced scores on the CDS by on average 44% (range 2-83.5%). Two patients could be classified as "full responders", four as "partial" and one a non-responder. Response usually occurred within the first 6 sessions. There were no significant adverse events. A randomized controlled clinical trial of VLPFC rTMS for DPD is warranted.
一句话概括: 右VLPFC rTMS可显著改善DPD症状，44%平均降低，安全耐受性好。
[5] Temporo-parietal junction stimulation in the treatment of depersonalization disorder
作者: Mantovani A.; Simeon D.; Urban N.; Allart A.; Bulow P.; Lisanby S.
年份: 2010
DOI: 10.1016/j.biopsych.2010.03.007
原文链接: [https://www.embase.com/search/results?subaction = viewrecord&id = L70129628&from = export http://dx.doi.org/10.1016/j.biopsych.2010.03.007](https://www.embase.com/search/results?subaction = viewrecord&id = L70129628&from = export)
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1016/j.biopsych.2010.03.007](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1016/j.biopsych.2010.03.007)
摘要（中文）: 12名DPD患者接受右侧TPJ低频rTMS治疗6周。3周后整体样本去人格化评分降低24%，5名完成6周治疗的患者症状改善68%，无明显不良反应。
摘要（英文）: Background: Depersonalization Disorder (DPD) is a condition for which no efficacious treatments exist. We present results of the first trial testing repetitive Transcranial Magnetic Stimulation (rTMS) effects on temporoparietal junction (TPJ), previously found to be hyperactive in DPD. Methods: Twelve DPD patients (M/F = 9/3; Mean Age = 33.6 years, S.D. = 12.9) were treated with inhibitory (1-Hz) rTMS to the TPJ for 6 weeks. Response to treatment was defined as a ≥ 50% decrease on the Cambridge Depersonalization Scale (CDS). Patients who showed at least 25% decrease on the CDS after 3 weeks of right TPJ stimulation received 3 more weeks of right TPJ rTMS to test whether additional rTMS might be beneficial. The others were crossed over to 3 weeks of left TPJ rTMS to test for a lateralized effect of rTMS on DPD. Results: After 3 weeks of right TPJ rTMS the entire sample showed 24% reduction in the CDS, from 114±41 to 87±47 (p = 0.002). In those patients (n = 5) who received 6 weeks of right TPJ rTMS, DPD symptoms showed 68% improvement, with a significant CDS total score decrease from 113±52 to 36±30 (p = 0.002). Four patients withdrew after the first 3 weeks; those who crossed over to left TPJ rTMS (n = 3) showed 7% improvement after 6 weeks. No side effects were noted in any patients. Conclusions: Low-frequency rTMS to the right TPJ resulted in significant clinical improvement in 5 out of 12 patients. A larger sample and a sham-controlled design will be needed to test the relevance of these promising although preliminary findings.
一句话概括: 右侧TPJ低频rTMS可显著改善DPD，6周治疗改善达68%。
[6] Treatment of a patient with depersonalization disorder with low frequency repetitive transcranial magnetic stimulation of the right temporo-parietal junction in a private practice setting
作者: Rachid F.
年份: 2017
DOI: 10.1097/PRA.0000000000000214
原文链接: [https://www.embase.com/search/results?subaction = viewrecord&id = L614870935&from = export http://dx.doi.org/10.1097/PRA.0000000000000214](https://www.embase.com/search/results?subaction = viewrecord&id = L614870935&from = export)
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1097/PRA.0000000000000214](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1097/PRA.0000000000000214)
摘要（中文）: 本案例报告描述了一名26岁DPD男性患者，病程6个月，对右侧TPJ低频rTMS治疗安全且显著有效。
摘要（英文）: Depersonalization disorder (DPD) is a debilitating dissociative condition with no proven treatments. Although the pathophysiology of DPD is poorly understood, there are reports of increased excitability of the prefrontal cortex in patients with this condition. The temporo-parietal junction may also play a major role in the conscious experience of the spatial unity of the normal self and body. Repetitive transcranial magnetic stimulation has been shown in some case studies to effectively treat this condition. This report describes an additional such case, a 26-year-old man with a 6-month history of DPD who responded safely and significantly to repetitive transcranial magnetic stimulation to the right temporo-parietal junction.
一句话概括: 右侧TPJ低频rTMS可安全有效治疗DPD。
[7] Treatment of depersonalization disorder with clomipramine
作者: Simeon D.; Stein D.; Hollander E.
年份: 1998
DOI: 10.1016/S0006-3223(98)00023-7
原文链接: [https://www.embase.com/search/results?subaction = viewrecord&id = L28389717&from = export http://dx.doi.org/10.1016/S0006-3223(98)00023-7](https://www.embase.com/search/results?subaction = viewrecord&id = L28389717&from = export)
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1016/S0006-3223(98)00023-7](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1016/S0006-3223(98)00023-7)
摘要（中文）: 8名DSM-III-R去人格化障碍患者进入双盲交叉试验，氯米帕明组2/7例显著改善，3例因不良反应早期退出。1例应答者在开放维持治疗4年期间症状保持几乎完全缓解，每次减药或换药均复发。氯米帕明可能是有效的治疗选择。
摘要（英文）: Background: Although there is a dire paucity of data on the pharmacologic treatment of depersonalization disorder, there have been a few reports in the literature suggesting that selective serotonin reuptake inhibitors may be of therapeutic benefit. In this study, we undertook to evaluate the efficacy of the potent serotonin reuptake inhibitor clomipramine in treating depersonalization. Methods: Eight subjects with DSM-III-R depersonalization disorder were entered into a double-blind crossover trial consisting of 8 weeks desipramine and 8 weeks clomipramine. Due to the very small size of the trial findings are presented descriptively. Results: Of 7 subjects who entered the clomipramine trial, two showed significant improvement in depersonalization. Three subjects dropped out early, unable to tolerate adverse effects. Of 6 subjects who entered the desipramine trial, 1 showed significant improvement in depersonalization. One clomipramine responder was subsequently followed in open maintenance treatment with clomipramine for 4 years, and her depersonalization symptoms remained in almost complete remission, with relapses upon each attempt to taper off or switch medication. Conclusions: Clomipramine may be a promising pharmacologic treatment for primary depersonalization disorder and warrants further investigation.
一句话概括: 氯米帕明可能对DPD有效，部分患者可获长期缓解。
[8] A placebo-controlled, cross-over trial of lamotrigine in depersonalization disorder
作者: Sierra M.; Phillips M.; Ivin G.; Krystal J.; David A.
年份: 2003
DOI: 10.1177/0269881103017001712
原文链接: [https://www.embase.com/search/results?subaction = viewrecord&id = L36373147&from = export http://dx.doi.org/10.1177/0269881103017001712](https://www.embase.com/search/results?subaction = viewrecord&id = L36373147&from = export)
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1177/0269881103017001712](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1177/0269881103017001712)
摘要（中文）: 9名DSM-IV去人格化障碍患者接受12周拉莫三嗪或安慰剂双盲交叉试验。拉莫三嗪并不显著优于安慰剂，9例患者中无1例对拉莫三嗪产生应答。拉莫三嗪作为单一药物治疗DPD似乎无效。
摘要（英文）: There is evidence to support the view that glutamate hyperactivity might be relevant to the neurobiology of depersonalization. We tested the efficacy of lamotrigine, which reduces glutamate release, as a treatment for patients with depersonalization disorder. A double-blind, placebo-controlled, cross-over design was used to evaluate 12 weeks of treatment of lamotrigine. Subjects comprised nine patients with DSM-IV depersonalization disorder. Changes on the Cambridge Depersonalization Scale and the Present State Examination depersonalization/derealization items were compared across the two cross-over periods. Lamotrigine was not significantly superior to placebo. None of the nine patients was deemed a responder to the lamotrigine arm of the cross-over. Lamotrigine does not seem to be useful as a sole medication in the treatment of depersonalization disorder.
一句话概括: 拉莫三嗪作为单一药物对DPD无效。
[9] Targeting temporal parietal junction for assessing and treating disembodiment phenomena: A systematic review of TMS effect on depersonalization and derealization disorders (DPD) and body illusions
作者: Orrù G.; Bertelloni D.; Cesari V.; Conversano C.; Gemignani A.
年份: 2021
DOI: 10.3934/Neuroscience.2021009
原文链接: http://www.aimspress.com/article/doi/10.3934/Neuroscience.2021009
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.3934/Neuroscience.2021009](https://pubmed.ncbi.nlm.nih.gov/?term = 10.3934/Neuroscience.2021009)
摘要（中文）: 本系统综述综合了TPJ的TMS治疗DPD和身体错觉的研究证据。8项研究符合纳入标准，结果表明针对TPJ的TMS是治疗DPD身体脱离现象的有前景技术。
摘要（英文）: The temporal-parietal junction (TPJ) is a key structure for the embodiment, term referred to as the sense of being localized within one's physical body and is a fundamental aspect of the self. On the contrary, the sense of disembodiment, an alteration of one's sense of self or the sense of being localized out of one's physical body, is a prominent feature in specific dissociative disorders, namely depersonalization/derealization disorders (DPD). The aims of the study were to provide: 1) a qualitative synthesis of the effect of Transcranial Magnetic Stimulation (TMS), taking into account its use for therapeutic and experimental purposes; 2) a better understanding on whether the use of TMS could support the treatment of DPD and other clinical conditions in which depersonalization and derealization are displayed. To identify suitable publications, an online search of the PubMed, Cochrane Library, Web of science and Scopus databases was performed using relevant search terms. In addition, an in-depth search was performed by screening review articles and the references section of each included articles. Our search yielded a total of 108 records through multiple databases searching and one additional record was identified through other sources. After duplicates removal, title and abstract reading, we retained 16 records for the assessment of eligibility. According to our inclusion criteria, we retained 8 studies. The selected studies showed that TMS targeting the TPJ is a promising technique for treating disembodiment phenomena DPD and for inducing reversible disembodiment states in healthy subjects. These data represent the first step towards a greater understanding of possible treatments to be used in disembodiment disorders. The use of TMS over the TPJ appears to be promising for treating disembodiment phenomena.
一句话概括: TMS靶向TPJ是治疗DPD身体脱离现象的有前景技术。
[10] Testing a neurobiological model of depersonalization disorder using repetitive transcranial magnetic stimulation
作者: Jay E.; Sierra M.; Van Den Eynde F.; Rothwell J.; David A.
年份: 2014
DOI: 10.1016/j.brs.2013.12.002
原文链接: [https://www.embase.com/search/results?subaction = viewrecord&id = L52959177&from = export http://dx.doi.org/10.1016/j.brs.2013.12.002](https://www.embase.com/search/results?subaction = viewrecord&id = L52959177&from = export)
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1016/j.brs.2013.12.002](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1016/j.brs.2013.12.002)
摘要（中文）: 17名耐药DPD患者和20名对照随机接受右侧VLPFC或TPJ单次rTMS。右侧VLPFC rTMS显著增加皮肤电导容量和自发波动，支持VLPFC活动增强与情绪麻木相关的模型。两种部位rTMS均降低去人格化评分，但与生理唤醒无关。
摘要（英文）: Background Depersonalization disorder (DPD) includes changes in subjective experiencing of self, encompassing emotional numbing. Functional magnetic resonance imaging (fMRI) has pointed to ventrolateral prefrontal cortex (VLPFC) inhibition of insula as a neurocognitive correlate of the disorder. Objective We hypothesized that inhibition to right VLPFC using repetitive transcranial magnetic stimulation (rTMS) would lead to increased arousal and reduced symptoms. Methods Patients with medication-resistant DSM-IV DPD (N = 17) and controls (N = 20) were randomized to receive one session of right-sided rTMS to VLPFC or temporo-parietal junction (TPJ). 1Hz rTMS was guided using neuronavigation and delivered for 15 min. Co-primary outcomes were: (a) maximum skin conductance capacity, and (b) reduction in depersonalization symptoms (Cambridge Depersonalization Scale (CDS) [state version]). Secondary outcomes included spontaneous fluctuations (SFs) and event-related skin conductance responses. Results In patients with DPD, rTMS to VLPFC led to increased electrodermal capacity, namely maximum skin conductance deflections. Patients but not controls also showed increased SFs post rTMS. Patients who had either VLPFC or TPJ rTMS showed a similar significant reduction in symptoms. Event-related electrodermal activity did not change. Conclusions A single session of right-sided rTMS to VLPFC (but not TPJ) significantly increased physiological arousal capacity supporting our model regarding the relevance of increased VLPFC activity to emotional numbing in DPD. rTMS to both sites led to reduced depersonalization scores but since this was independent of physiological arousal, this may be a non-specific effect. TMS is a potential therapeutic option for DPD; modulation of VLPFC, if replicated, is a plausible mechanism.
一句话概括: 右VLPFC rTMS增加生理唤醒支持神经生物学模型，两部位均可改善症状。
[11] Combined Therapies–rTMS meets CBT. Novel approach for the treatment of Derealization/Depersonalization Syndrome
作者: Wulf L.; Palm U.; Padberg F.
年份: 2019
DOI: 10.1016/j.encep.2019.04.046
原文链接: [https://www.embase.com/search/results?subaction = viewrecord&id = L2002053447&from = export http://dx.doi.org/10.1016/j.encep.2019.04.046](https://www.embase.com/search/results?subaction = viewrecord&id = L2002053447&from = export)
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1016/j.encep.2019.04.046](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1016/j.encep.2019.04.046)
摘要（中文）: 4名DDS患者随机分配至右侧VLPFC或TPJ rTMS协议，同时接受CBT（正念、暴露、肌肉放松和运动）。两种方案均耐受良好，部分患者症状显著改善，暴露练习和运动获益最大。
摘要（英文）: Background: Depersonalization-derealization-syndrome (DDS) is generally associated with a state of self-alienation. The symptoms are experienced i-dystonically and consciously as a discrete and altered condition to the previous experience. There are hardly any well-researched explanatory models for pathogenesis or efficient treatment strategies. Newer approaches include cognitive-behavioral-therapy (CBT) and therapy with transcranial magnetic stimulation (rTMS). Against this background the idea arose to combine rTMS with CBT to find novel strategies in the treatment of DDS. Therefore the feasibility of a combination therapy, based on the concept of Donse et al. (2018) [1], will be investigated within a case series. Study design: Four patients with a leading DDS diagnosis were recruited and randomly assigned to a treatment protocol: right ventrolateral prefrontal cortex (rVLPFC) vs. temporoparietal junction (TPJ). All patients received 15 rTMS stimulation over three weeks. The stimulation parameters differed depending on the treatment protocol. Group 1 receives the so-called Mantovani-protocol: 1 Hz, 30 minutes (1800 pulses) with a 100% intensity of the MEP above the right TPJ. Group 2 received the so-called Jay-protocol: 1 Hz, 15 minutes (900 pulses) with a 110% intensity of the MEP above the right VLPFK. At the same time, all patients received CBT, which include exercises for mindfulness, confrontation, muscle relaxation and sport. Results: The rTMS treatment was tolerated well. In terms of psychotherapeutic intervention, they have benefited most from the confrontation exercises and from sport. The cut-off value for the DDS symptoms is a score of 40 and higher. The table shows a reduction in symptoms from pre to post rating for pat. 2 and for pat. 4 even under the cut-off in the Mantovani-protocol. As well as a reduction from post to FU for Pat. 1 and 3. using the Jay-protocol. Pat. 3 shows an increase of symptoms from pre to post measures but...
一句话概括: rTMS联合CBT治疗DDS可行，暴露练习和运动获益最大。
[12] Safety and effectiveness of transcutaneous auricular vagus nerve stimulation on patients with depersonalization-derealization disorder: Study protocol for a randomized controlled trial
作者: Zhao Y.; Zheng S.; Zhu H.; Yin D.; Fang M.; Jia H.
年份: 2024
DOI: 10.1186/s13063-024-08658-w
原文链接: 无
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1186/s13063-024-08658-w](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1186/s13063-024-08658-w)
摘要（中文）: 本研究方案探讨经耳迷走神经刺激（taVNS）治疗DPD的安全性和有效性。DPD患者随机分配至实验组（真刺激）或对照组（伪刺激）6周治疗，通过症状评分、抑郁焦虑认知功能和社会功能评估疗效。
摘要（英文）: BACKGROUND: Depersonalization-derealization disorder (DPD) is a complex psychiatric condition marked by profound and often relentless feelings of detachment from one's self and surroundings. Transcranial electrical stimulation (taVNS) holds promise as a potential therapeutic approach for DPD. This study aims to investigate the safety and efficacy of taVNS in treating DPD. METHODS: DPD patients were recruited as research subjects and randomly allocated to the experimental and control groups, with the former receiving active-taVNS treatment and the latter receiving sham stimulation treatment for 6 weeks. The efficacy of taVNS in treating DPD was evaluated by comparing scores for DPD symptoms, depression and anxiety symptoms, cognitive function, and social function before and after treatment between the two groups. The safety of taVNS in treating DPD was assessed by comparing general safety assessment results between the two groups of DPD patients. DISCUSSION: This study will assess taVNS as a potential treatment for DPD, evaluating its safety, efficacy, and impact on patient outcomes and societal burden. TRIAL REGISTRATION: Chinese Clinical Trial Registry, ChiCTR2300078183, Registered on 30 November, 2023, https://www.chictr.org.cn/showproj.html?proj = 206119.
一句话概括: taVNS治疗DPD的随机对照试验方案，旨在评估其安全性有效性。
[13] Online structured dance/movement therapy reduces bodily detachment in depersonalization-derealization disorder
作者: Millman L.; Hunter E.; Terhune D.; Orgs G.
年份: 2023
DOI: 10.1016/j.ctcp.2023.101749
原文链接: 无
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1016/j.ctcp.2023.101749](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1016/j.ctcp.2023.101749)
摘要（中文）: 本研究开发两种在线舞蹈任务（身体觉察训练和舞蹈运动）以减轻DDD患者的身体脱离。31名DDD患者和29名对照交叉完成两种任务。两种任务均降低DDD组症状，舞蹈运动增加正念更明显。
摘要（英文）: BACKGROUND: Depersonalization-derealization disorder (DDD) is a dissociative disorder encompassing pronounced disconnections from the self and from external reality. As DDD is inherently tied to a detachment from the body, dance/movement therapy could provide an innovative treatment approach. MATERIALS AND METHODS: We developed two online dance tasks to reduce detachment either by training body awareness (BA task) or enhancing the salience of bodily signals through dance exercise (DE task). Individuals with DDD (n = 31) and healthy controls (n = 29) performed both tasks individually in a cross-over design. We assessed symptom severity (Cambridge Depersonalization Scale), interoceptive awareness (Multidimensional Assessment of Interoceptive Awareness - II), mindfulness (Five Facet Mindfulness Questionnaire), and body vigilance (Body Vigilance Scale) before, during and after the tasks. RESULTS: At baseline, individuals with DDD exhibited elevated depersonalization-derealization symptoms alongside lower levels of interoceptive awareness and mindfulness compared to controls. Both tasks reduced symptoms in the DDD group, though dance exercise was perceived as easier. The DE task increased mindfulness in those with DDD more than the BA task, whereas controls showed the opposite pattern. In the DDD group, within-subject correlations showed that lower levels of symptoms were associated with task-specific elevations in interoceptive awareness and mindfulness. CONCLUSION: Individual and structured dance/movement practice, performed at home without an instructor present, offers an effective tool to reduce symptoms in DDD and can be tailored to address specific cognitive components of a mindful engagement with the body.
一句话概括: 在线舞蹈/运动疗法可有效减轻DDD患者的身体脱离症状。
[14] Mindfulness-Based Cognitive Therapy in Depersonalization-Derealization disorder: A Case Report
作者: Mishra S.; Das N.; Mohapatra D.; Mishra B.
年份: 2022
DOI: 10.1177/02537176211040259
原文链接: 无
PubMed: [https://pubmed.ncbi.nlm.nih.gov/?term=10.1177/02537176211040259](https://pubmed.ncbi.nlm.nih.gov/?term = 10.1177/02537176211040259)
摘要（中文）: 暂无摘要
摘要（英文）: 暂无摘要
一句话概括: 正念认知疗法治疗DPD的案例报告。
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