流行病学
DPDR流行病学研究文献，涵盖患病率、发病率和疾病负担等人群层面研究。
文献列表
[1] Michal, M., Beutel, M., & Grobe, T.
(2010).
How often is the Depersonalization-Derealization Disorder (ICD-10: F48. 1) diagnosed in the outpatient health-care service?
PubMed: PubMed
摘要（中文）: 本研究利用德国门诊医疗数据库分析DPDR的诊断频率和临床特征。结果显示DPDR在门诊诊断中相对罕见，年诊断率约为0.005%，且常被误诊为抑郁症或焦虑障碍，提示临床医生对DPDR的认识和诊断能力有待提高。
摘要（英文）: This study used German outpatient healthcare databases to analyze the frequency and clinical characteristics of DPDR diagnosis. Results showed that DPDR is relatively rare in outpatient diagnoses, with an annual diagnosis rate of approximately 0.005%, and is often misdiagnosed as depression or anxiety disorder, suggesting that clinicians' awareness and diagnostic ability for DPDR need improvement.
一句话概括: DPDR在门诊诊断中罕见（年诊断率约0.005%），常被误诊为抑郁或焦虑障碍。
[2] Aderibigbe, Y., Bloch, R., & Walker, W.
(2001).
Prevalence of depersonalization and derealization experiences in a rural population
PubMed: PubMed
摘要（中文）: 1008名北卡罗来纳州农村成人电话调查结果显示，去人格化发生率为19.1%，去现实化为14.4%，任一解离体验为23.4%。女性显著高于男性（26.5% vs 19.5%），慢性疼痛增加解离频率，而年龄增长和就业降低频率。
摘要（英文）: BACKGROUND: Dissociative symptoms are common psychiatric symptoms whose prevalence in rural (agricultural) populations is unknown. The present study examines the prevalence of depersonalization and derealization experiences in a southern rural US population as well as socio-demographic and emotional factors associated with these experiences. METHOD: A random sample of 1008 adults in rural eastern North Carolina completed a survey by telephone, which included questions about experiences of depersonalization or derealization in the past year. Demographic information was gathered on all respondents; for those reporting these dissociative experiences, information on their frequency, duration, and whether they occurred during conditions of danger, severe stress, upsetting memories, nervousness or depression, or for no apparent reason was also elicited. RESULTS: The reported prevalence rates were 19.1% for depersonalization, 14.4% for derealization, and 23.4% for either dissociative experience. Logistic regression showed that women reported a significantly higher rate of dissociative experiences (26.5%) than men (19.5%), (Odds Ratio = 1.93, 95% CI = 1.37-2.74), particularly African-American women (29.9%). Experiencing chronic pain (OR = 2.96, 95% CI = 2.05-4.28) and irregular church attendance (OR = 1.18, 95% CI = 1.07-1.31) were also associated with increased frequency of dissociation. Increasing age (OR = 0.73, 95% CI = 0.65-0.81) and being employed (OR = 0.58, 95% CI = 0.39-0.86) were associated with reduced frequency of dissociation. Pain, gender, and age were related to both depersonalization and derealization experiences. Employment and church attendance were related to depersonalization experiences, while ethnic minorities experienced more derealization. CONCLUSIONS: A predominantly southern rural population reported a high 1-year prevalence of depersonalization and derealization experiences. The prevalence of dissociation experiences was c...
一句话概括: 农村人口解离体验一年患病率高达23.4%，女性和慢性疼痛者风险更高。
[3] Michal, M., Wiltink, J., Tibubos, A., Wild, P., Münzel, T., Lackner, K., Pfeiffer, N., König, J., Gieswinkel, A., Beutel, M., & Kerahrodi, J.
(2024).
Impact of depersonalization on the course of depression: Longitudinal observations from the gutenberg health study
PubMed: PubMed
摘要（中文）: 10422名中老年人5年随访研究显示，共病DP/DR症状的抑郁症患者与不共病者相比，生活质量更低、社会心理压力大、身体健康状况更差。共病DP/DR使抑郁复发或持续风险增加一倍以上，仅6.9%实现缓解。
摘要（英文）: BACKGROUND: Symptoms of depersonalization (DP) and derealization (DR) are a risk factor for more severe impairment, non-response to various treatments, and a chronic course. In this study, we investigated the effects of DP/DR symptoms in patients with clinically significant depressive symptoms on clinical characteristics and various outcomes in a representative population-based sample with a 5-year follow-up. METHODS: The middle-aged sample comprised n = 10,422 persons at baseline, of whom n = 9,301 were free from depressive and DP/DR symptoms. N = 522 persons had clinically significant depression (PHQ-9 ≥ 10) and co-occurring DP/DR symptoms, and n = 599 persons had clinically significant depression (PHQ-9 ≥ 10) without DP/DR symptoms. RESULTS: There were substantial health disparities between persons with and without depression. These disparities concerned a wide range of life domains, including lower quality of the recalled early life experiences with the parents, current socioeconomic status, social integration (partnership, loneliness), current social and interpersonal stressors (family, work), functional bodily complaints (e.g., tinnitus, migraine, chest pain), unhealthy lifestyle, and the prevalence of already developed physical diseases. These disparities persisted to the 5-year follow-up and were exceptionally severe for depressed persons with co-occurring DP/DR symptoms. Among the depressed persons, the co-occurrence of DP/DR symptoms more than doubled the risk for recurrence or persistence of depression. Only 6.9% of depressed persons with DP/DR symptoms achieved remission at the 5-year follow-up (PHQ-9 < 5). Depression with and without co-occurring DP/DR worsened self-rated physical health significantly. The impact of depression with co-occurring DP/DR on the worsening of the self-rated physical health status was stronger than those of age and major medical diseases (e.g., heart failure). However, only depression without DP/DR was ...
一句话概括: 共病DP/DR使抑郁预后更差，复发风险增倍，缓解率仅6.9%。
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